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I'm not sure of the dates but I think it was only this year that doctors became aware of the interaction between Prilosec and Plavix. You would be better off taking warfarin than both plavix and aspirin. Plavix is used to treat the following conditions: Acute Coronary Syndrome, Heart Attack, Ischemic Stroke, Ischemic Stroke, Prophylaxis. I personally take a blood thinner (Plavix) from having two blood clots and I don't drink anything. As stated in the Plavix prescribing information, studies have shown that formation of clopidogrel's active metabolite may be affected by patients with reduced CYP2C19 function or by drugs that inhibit CYP2C19, including certain proton pump inhibitors such as omeprazole. We have previously raised concerns about the efficacy and safety of prasugrel, as well as serious flaws in TRITON-TIMI 38, the Phase 3 study comparing prasugrel with clopidogrel (PLAVIX) in patients with ACS.

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